How to Manage COVID-19 Vaccine Stored at +2 to +8 ºC?

 

 

 

Storage Condition +2 to +8 °C:

 

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What TO Do:

  • Ensure that all vaccines and diluents are kept in their original secondary packaging and are clearly labeled.
  • Whenever possible, keep both vaccine and diluent in the same refrigeration unit.
  • Monitor and record the temperature more frequently (>2x/day).
  • Investigate any fluctuation of temperature and correct the root cause as soon as possible.
  • Use a labeled container or tray for loose unopened vaccine vials to facilitate inventory.
  • Follow the “first manufacture/expiry, first out” principle:
    • Use first the vaccine with earlier manufacturing/expiry date and/or darker VVM (if available) to minimize wastage.
  • Record and discard all wastage of vaccines immediately according to national guidelines.
  • Review and update contingency plan in case of power failure, equipment breakdown, or cold chain breach.

Storage Condition +2 to +8 °C:

 

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What NOT to Do:

  • Do not return opened vaccine vials to the cold chain. Discard them according to existing standard operating procedures.
  • Never put vaccines in contact with or close to the evaporator plate in the refrigerator.
  • Since heat/freeze sensitivity information is not fully known, keep vaccine vials in the middle section, especially if the refrigeration unit has a freezer compartment, to avoid freezing the vaccine.
  • Do not keep reconstituted vaccines for more than 6 hours after opening or after the end of an immunization session, whichever comes first – this may change once vaccine stability information is available.