Prevention and Management of AEFI
How Can You Prevent Immunization Error-Related AEFI?
- Do not store and/or pack other diluents or medications together with the COVID-19 vaccine.
- Always check the labels of vaccines and diluents before reconstitution. Vaccines and diluents should be from the same manufacturer.
- Follow manufacturer’s recommendations on storage, vaccine preparation, route and technique of administration, and contraindications/precautions.
- Draw the AD syringe just before vaccination.
- Do not touch the needle.
- Do not touch the rubber cap of the vaccine vial.
- If reconstituted, never carry vaccines from one place to another.
- Do not cover the vaccine carrier with the lid while the reconstituted vaccine vial is in the foam pad.
- Discard the vaccine if it was reconstituted before the maximum recommended time or at the end of the session, whichever comes first.
- When in doubt, contact your supervisor for clarification. Do not hesitate to report issues or concerns when identified.
Fainting (Syncope)
- Individuals are at risk of falls due to syncope during and after vaccine administration.
- To decrease this risk, have a place for patients to sit down while they are vaccinated and be ready to lower them to a lying position, if needed.
- Vaccinators are encouraged to observe the vaccinated person (sitting or lying down) for:
- 30 minutes in people with a history of a severe allergic reaction (anaphylaxis) due to any cause.
- 15 minutes for all other people to monitor for any immediate adverse reactions.
Allergic Reaction (Anaphylaxis)
- Anaphylactic reactions in people receiving the COVID-19 vaccine outside of clinical trials have been reported.
- In general anaphylaxis is a very rare but severe and potentially fatal reaction.
- Proper diagnosis and urgent treatment and management are essential.
- When sudden loss of consciousness occurs >5–10 minutes after immunization, anaphylaxis should be considered as a possible diagnosis, in addition to fainting (vasovagal syncope).
- Appropriate medical treatment used to manage immediate allergic reactions e.g., epinephrine (Adrenaline) must be immediately available in the event an acute anaphylactic reaction occurs following administration of the vaccine.