6.6 Air versus oxygen

The use of oxygen or air in newborn resuscitation remains controversial as there are concerns about oxygen toxicity and the development of neonatal encephalopathy.

It has been shown that newborn infants may be resuscitated effective with either air or 100% oxygen; the most important intervention is to aerate the lungs to allow gas exchange to occur. High concentrations of oxygen should be avoided if possible, particularly in preterm infants.

If the baby fails to improve when resuscitated with air, or if the baby remains cyanosed, than supplementary oxygen should be considered. A baby who has arrested will respond more quickly to resuscitation with 100% oxygen rather than room air.

Key point on Neonatal resuscitation 

PPV( Positive Pressure Ventilation ) 

-Rising heart rate 

-Chest rise 

-Breath sounds 

-Rising O2 saturation 

Chest compression 

DO NOT Start Chest compressions unless baby has received 30 sec of 

Effective ventilation and HR < 60 

CPR (Cardio-Pulmonary Resusitation) 


Drugs 

epinephrine 

• Used if heart rate is < 60 

After 

▫ 30 sec of PPV and 

▫ 45-60 sec of PPV and chest compressions 

• Epinephrine 1:10,000 solution (0.1mg/ml) 

▫ 0.1-0.3 ml/kg IV 

▫ 0.5-1.0 ml/kg ETT 

▫ 1.0 ml saline flush 

• Continue CPR 

• Reassess after 60 sec 

• May repeat dose q 5 min 


Volume resuscitation 

▫ 10 ml/kg IV given over 5-10 min